Interactor 1: DPH1 (P49958)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)
Gene: dph-1
Interactor 2: DPH2 (Q09454)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)
Gene: dph-2
Species: Caenorhabditis elegans
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.723 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19123269 |
| Identification Methods | two hybrid, two hybrid array, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Diphthamide_syn~Diphthamide_syn |
| Common GO terms | GO:0017183 - protein histidyl modification to diphthamide GO:0032991 - protein-containing complex GO:0046872 - metal ion binding GO:0051539 - 4 iron, 4 sulfur cluster binding GO:0090560 - 2-(3-amino-3-carboxypropyl)histidine synthase activity |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
