HitPredict

Interactor 1: GBG4 (P50153)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
Gene: Gng4

Interactor 2: GNB5 (P62881)
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
Gene: GNB5

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	8636150
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	G-gamma~WD40
Common GO terms	GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 75 Mm			1 395
+	Hs
		154666 GBG4_HUMAN (1-75): 1.41e-30: 103: 98.67		GNB5_HUMAN (1-395): 1.88e-115: 343: 99.24
+	Hs
		154672 GBG3_HUMAN (1-75): 7.91e-30: 102: 68.00		GNB5_HUMAN (1-395): 1.88e-115: 343: 99.24
+	Hs
		154670 GBG2_HUMAN (5-75): 1.22e-28: 99: 76.06		GNB5_HUMAN (1-395): 1.88e-115: 343: 99.24
+	Hs
		154700 GBG8_HUMAN (7-75): 3.45e-25: 90.1: 59.42		GNB5_HUMAN (1-395): 1.88e-115: 343: 99.24
+	Hs
		560864 GBG4_HUMAN (1-75): 1.41e-30: 103: 98.67		GBB3_HUMAN (7-309): 3.15e-58: 194: 16.45
+	Hs
		560872 GBG3_HUMAN (1-75): 7.91e-30: 102: 68.00		GBB3_HUMAN (7-309): 3.15e-58: 194: 16.45
+	Hs
		837672 GBG4_HUMAN (1-75): 1.41e-30: 103: 98.67		GBB1_HUMAN (7-309): 7.94e-57: 191: 16.56
+	Hs
		560868 GBG2_HUMAN (5-75): 1.22e-28: 99: 76.06		GBB3_HUMAN (7-309): 3.15e-58: 194: 16.45
+	Hs
		920932 GBG3_HUMAN (1-75): 7.91e-30: 102: 68.00		GBB1_HUMAN (7-309): 7.94e-57: 191: 16.56
+	Hs
		837682 GBG4_HUMAN (1-75): 1.41e-30: 103: 98.67		GBB4_HUMAN (7-309): 8.61e-56: 188: 17.86
+	Hs
		887096 GBG2_HUMAN (5-75): 1.22e-28: 99: 76.06		GBB1_HUMAN (7-309): 7.94e-57: 191: 16.56
+	Bt
		920925 GBG2_BOVIN (5-75): 1.22e-28: 99: 76.06		GBB1_BOVIN (7-309): 7.94e-57: 191: 16.56
+	Mm
		921088 GBG2_MOUSE (5-75): 1.22e-28: 99: 76.06		GBB1_MOUSE (7-309): 7.94e-57: 191: 16.56
+	Hs
		929157 GBG3_HUMAN (1-75): 7.91e-30: 102: 68.00		GBB4_HUMAN (7-309): 8.61e-56: 188: 17.86
+	Hs
		887126 GBG2_HUMAN (5-75): 1.22e-28: 99: 76.06		GBB4_HUMAN (7-309): 8.61e-56: 188: 17.86
+	Hs
		560895 GBG8_HUMAN (7-75): 3.45e-25: 90.1: 59.42		GBB3_HUMAN (7-309): 3.15e-58: 194: 16.45
+	Hs
		837673 GBG4_HUMAN (1-75): 1.41e-30: 103: 98.67		GBB2_HUMAN (320-395): 1.54e-11: 67.1: 17.11
+	Hs
		921516 GBG3_HUMAN (1-75): 7.91e-30: 102: 68.00		GBB2_HUMAN (320-395): 1.54e-11: 67.1: 17.11
+	Mm
		666790 GBG4_MOUSE (1-75): 4.88e-30: 102: 100.00		GBB4_MOUSE (56-175): 1.16e-10: 64.4: 13.33
+	Hs
		887097 GBG2_HUMAN (5-75): 1.22e-28: 99: 76.06		GBB2_HUMAN (320-395): 1.54e-11: 67.1: 17.11