HitPredict

Interactor 1: MEOX2 (P50222)
Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2)
Gene: MEOX2

Interactor 2: ERF (P50548)
ETS domain-containing transcription factor ERF (Ets2 repressor factor) (PE-2)
Gene: ERF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0043565 - sequence-specific DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 304 Hs			1 548
+	Hs
		840383 Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36		ERF_HUMAN (1-548): 2.67e-75: 250: 100.00
+	Hs
		794528 MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00		ETV4_HUMAN (1-168): 9.4e-41: 155: 31.77
+	Hs
		794549 Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36		ETV4_HUMAN (1-168): 9.4e-41: 155: 31.77
+	Hs
		541983 PIT1_HUMAN (1-252): 5.17e-36: 132: 15.81		ETS1_HUMAN (14-131): 5.65e-45: 166: 48.31
+	Dm
		949985 UBX_DROME (40-248): 2.12e-30: 120: 24.88		ELG_DROME (16-145): 1.49e-43: 163: 41.54
+	Hs
		882119 GSC_HUMAN (37-284): 4.31e-31: 118: 17.93		FLI1_HUMAN (2-204): 5.44e-44: 163: 34.48
+	Ce
		484983 MAB5_CAEEL (143-270): 4.37e-29: 112: 31.25		Q400M2_CAEEL (9-136): 1.83e-43: 161: 33.33
+	Hs
		446866 HXD4_HUMAN (50-247): 1.07e-30: 117: 24.50		ETV4_HUMAN (1-168): 9.4e-41: 155: 31.77
+	Dm
		669754 Q9XZU0_DROME (179-300): 2.75e-29: 116: 27.05		ETS3_DROME (2-210): 9.65e-39: 150: 34.76
+	Ce
		109652 MAB5_CAEEL (143-270): 4.37e-29: 112: 31.25		H2KYY1_CAEEL (9-136): 1.61e-40: 153: 33.33
+	Dm
		669726 Q8T0V5_DROME (179-300): 5.19e-29: 115: 27.05		ETS3_DROME (2-210): 9.65e-39: 150: 34.76
+	Dm
		669733 Q9VCY0_DROME (138-254): 5.62e-30: 113: 41.32		ETS3_DROME (2-210): 9.65e-39: 150: 34.76
+	Dm
		669728 Q9U984_DROME (138-254): 5.81e-29: 110: 41.32		ETS3_DROME (2-210): 9.65e-39: 150: 34.76
+	Hs
		567877 HXB9_HUMAN (21-252): 3.38e-31: 118: 24.57		FEV_HUMAN (10-219): 1.19e-36: 138: 33.65
+	Hs
		584241 EMX1_HUMAN (68-260): 2.59e-31: 120: 27.50		ELK1_HUMAN (26-452): 5.74e-34: 135: 19.68
+	Hs
		785344 MNX1_HUMAN (180-253): 1.37e-14: 75.5: 54.05		ELK3_HUMAN (41-206): 5.54e-43: 160: 30.95
+	Hs
		837772 MNX1_HUMAN (180-253): 1.37e-14: 75.5: 54.05		ETV7_HUMAN (7-143): 3.2e-36: 139: 25.36
+	Hs
		837769 MNX1_HUMAN (180-253): 1.37e-14: 75.5: 54.05		FEV_HUMAN (10-219): 1.19e-36: 138: 33.65
+	Mm
		980986 EMX1_MOUSE (64-260): 6.15e-33: 123: 26.50		SPDEF_MOUSE (19-106): 3.16e-12: 69.7: 48.35
+	Hs
		201848 HXA2_HUMAN (63-302): 6.17e-30: 118: 20.93		SYNJ1_HUMAN (231-487): 2.78e-12: 71.8: 13.21