HitPredict

Interactor 1: GDIB (P50395)
Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)
Gene: GDI2

Interactor 2: RAB2B (Q8WUD1)
Ras-related protein Rab-2B (EC 3.6.5.2)
Gene: RAB2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.802

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005794 - Golgi apparatus GO:0015031 - protein transport GO:0016192 - vesicle-mediated transport GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 216
+	Hs
		838673 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB8B_HUMAN (2-198): 1.07e-96: 281: 45.18
+	Hs
		678381 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB8B_HUMAN (2-198): 1.07e-96: 281: 45.18
+	Hs
		678377 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB2B_HUMAN (1-216): 1.82e-92: 271: 100.00
+	Hs
		838617 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB2A_HUMAN (1-216): 2.31e-86: 256: 82.87
+	Hs
		838625 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB1A_HUMAN (3-216): 9.52e-84: 249: 43.93
+	Hs
		678338 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB2A_HUMAN (1-216): 2.31e-86: 256: 82.87
+	Hs
		838621 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB14_HUMAN (3-215): 4.02e-82: 245: 55.87
+	Hs
		838683 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB1B_HUMAN (3-216): 1.37e-82: 245: 42.52
+	Hs
		838647 GDIB_HUMAN (1-445): 0: 722: 100.00		RB11B_HUMAN (3-216): 7.59e-82: 244: 46.73
+	Mm
		838709 GDIA_MOUSE (1-444): 0: 717: 87.39		RAB1A_MOUSE (3-216): 9.52e-84: 249: 43.93
+	Hs
		838624 GDIB_HUMAN (1-445): 0: 722: 100.00		RB11A_HUMAN (3-216): 1.65e-81: 243: 46.26
+	Hs
		678344 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB1A_HUMAN (3-216): 9.52e-84: 249: 43.93
+	Hs
		678341 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB14_HUMAN (3-215): 4.02e-82: 245: 55.87
+	Hs
		678359 GDIA_HUMAN (1-444): 0: 714: 86.49		RB11B_HUMAN (3-216): 7.59e-82: 244: 46.73
+	Hs
		678343 GDIA_HUMAN (1-444): 0: 714: 86.49		RB11A_HUMAN (3-216): 1.65e-81: 243: 46.26
+	Hs
		591772 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB4A_HUMAN (2-188): 8.55e-74: 224: 58.29
+	Hs
		591751 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB4A_HUMAN (2-188): 8.55e-74: 224: 58.29
+	Hs
		678337 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB4B_HUMAN (2-188): 5.85e-73: 221: 57.75
+	Hs
		838616 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB8A_HUMAN (2-196): 8.26e-61: 190: 46.19
+	Hs
		678336 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB8A_HUMAN (2-196): 8.26e-61: 190: 46.19