HitPredict

Interactor 1: SERPH (P50454)
Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47)
Gene: SERPINH1

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12577067
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 217
+	Hs
		839703 SERPH_HUMAN (1-418): 7.1e-152: 438: 100.00		VAV3_HUMAN (1-212): 1.16e-43: 157: 22.00
+	Hs
		782753 SPB4_HUMAN (41-409): 2.8e-150: 433: 26.02		CSK_HUMAN (2-139): 3.92e-24: 100: 36.24
+	Hs
		548664 SERPH_HUMAN (1-418): 7.1e-152: 438: 100.00		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		839664 SERPH_HUMAN (1-418): 7.1e-152: 438: 100.00		Q96D37_HUMAN (2-60): 8.82e-15: 74.6: 42.37
+	Hs
		397006 PAI2_HUMAN (43-409): 3.39e-150: 433: 25.36		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		397004 PAI2_HUMAN (43-409): 3.39e-150: 433: 25.36		YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91
+	Hs
		433287 SPB4_HUMAN (41-409): 2.8e-150: 433: 26.02		YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91
+	Hs
		548731 SPA12_HUMAN (5-411): 3.98e-144: 418: 23.28		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37