HitPredict

Interactor 1: MLC (P50456)
DNA-binding transcriptional repressor Mlc (Making large colonies protein) (Membrane linked control)
Gene: MLC

Interactor 2: PTGCB (P69786)
PTS system glucose-specific EIICB component (EIICB-Glc) (EII-Glc) [Includes: Glucose permease IIC component (PTS system glucose-specific EIIC component); Glucose-specific phosphotransferase enzyme IIB component (EC 2.7.1.199) (PTS system glucose-specific EIIB component)]
Gene: ptsG

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.90 0.749

The method score is based on:

Property Details
Experiments 18319344, 18067539
Identification Methods x-ray crystallography, surface plasmon resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PTS_EIIB~ROK
Common GO terms GO:0006355 - regulation of DNA-templated transcription
GO:0016020 - membrane
Homologous interactions 0

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Last updated: 15 Jul 2024