HitPredict

Interactor 1: LHX2 (P50458)
LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2)
Gene: LHX2

Interactor 2: SSBP3 (Q9BWW4)
Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein)
Gene: SSBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	30833792, 33961781, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Hs			1 388
+	Mm
		1321929 LHX2_MOUSE (1-406): 2.05e-98: 300: 99.02		SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00
+	Hs
		110821 H7C0H1_HUMAN (4-406): 7.05e-91: 282: 98.05		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		839818 LHX2_HUMAN (1-406): 2.55e-97: 298: 100.00		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		1314903 LHX9_HUMAN (1-406): 3.73e-76: 243: 61.58		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Mm
		1321891 LHX2_MOUSE (1-406): 2.05e-98: 300: 99.02		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Mm
		1321926 LHX9_MOUSE (1-406): 3.76e-74: 238: 61.33		SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00
+	Hs
		839725 LHX2_HUMAN (1-406): 2.55e-97: 298: 100.00		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		1314654 LHX9_HUMAN (1-406): 3.73e-76: 243: 61.58		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		839836 LHX2_HUMAN (1-406): 2.55e-97: 298: 100.00		CHD7_HUMAN (99-332): 1.72e-32: 131: 17.60
+	Mm
		1112385 LHX9_MOUSE (1-406): 3.76e-74: 238: 61.33		Q3U4B1_MOUSE (1-388): 1.81e-48: 169: 62.66
+	Mm
		1321890 LHX9_MOUSE (1-406): 3.76e-74: 238: 61.33		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		903773 LMO4_HUMAN (33-186): 6.88e-53: 175: 37.58		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		822674 LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		903772 LMO4_HUMAN (33-186): 6.88e-53: 175: 37.58		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		822672 LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Mm
		1321889 LMX1A_MOUSE (27-402): 3.01e-51: 178: 25.33		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Mm
		903801 LMO4_MOUSE (33-186): 6.88e-53: 175: 37.58		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		903700 LMO4_HUMAN (33-186): 6.88e-53: 175: 37.58		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		822624 LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		297853 LMO4_HUMAN (33-186): 6.88e-53: 175: 37.58		SC24D_HUMAN (95-332): 4.93e-11: 66.4: 20.23