HitPredict

Interactor 1: MXI1 (P50539)
Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11)
Gene: MXI1

Interactor 2: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.578

Property	Details
Experiments	25416956, 32296183
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 228 Hs			1 236
+	Hs
		484581 MXI1_HUMAN (1-228): 1.73e-90: 267: 100.00		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Hs
		1189419 MAD3_HUMAN (8-187): 8.14e-48: 158: 48.91		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		484695 MAD3_HUMAN (8-187): 8.14e-48: 158: 48.91		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Hs
		348008 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		TEN2_HUMAN (107-233): 2.51e-20: 91.2: 20.31
+	Dm
		422973 X2JDM5_DROME (32-152): 4.75e-34: 130: 27.05		NOTCH_DROME (10-236): 6.06e-15: 75.8: 21.99
+	Hs
		348223 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		NOTC3_HUMAN (12-198): 1.58e-11: 65.5: 29.67
+	Hs
		296631 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		SLIT2_HUMAN (68-185): 2.64e-10: 62: 32.52