HitPredict

Interactor 1: MXI1 (P50539)
Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11)
Gene: MXI1

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25515538, 29507620
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0046983 - protein dimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 228 Hs			1 542
+	Hs
		840229 MXI1_HUMAN (1-228): 1.73e-90: 267: 100.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		348277 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		898218 MAX_HUMAN (60-166): 6.51e-12: 63.3: 19.63		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Mm
		348444 MYC_MOUSE (27-150): 2.88e-37: 136: 28.03		FBXW7_MOUSE (18-424): 2.01e-73: 249: 20.29
+	Hs
		347517 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		346159 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		LIS1_HUMAN (276-542): 4.94e-75: 245: 28.43
+	Hs
		379688 MYCN_HUMAN (26-148): 3.93e-34: 128: 23.70		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		898168 MAX_HUMAN (60-166): 6.51e-12: 63.3: 19.63		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		196936 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		PRP4_HUMAN (320-536): 4.83e-42: 159: 22.13
+	Hs
		267729 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		TAF5L_HUMAN (369-541): 8.73e-29: 122: 16.11
+	Hs
		346638 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		TBL3_HUMAN (237-531): 4.06e-24: 108: 24.46
+	Hs
		267736 MYCL_HUMAN (25-149): 2.49e-28: 111: 22.58		TAF5L_HUMAN (369-541): 8.73e-29: 122: 16.11
+	Hs
		346404 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		379200 MYCN_HUMAN (26-148): 3.93e-34: 128: 23.70		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		607803 USF1_HUMAN (39-162): 5.04e-33: 123: 22.31		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		348035 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		NLE1_HUMAN (125-224): 6.61e-09: 60.3: 6.00
+	Dm
		1375911 MYC_DROME (64-153): 1.73e-21: 94.1: 24.47		FBXW7_DROME (428-541): 1.36e-21: 101: 29.57
+	Hs
		267750 MAX_HUMAN (60-166): 6.51e-12: 63.3: 19.63		TAF5L_HUMAN (369-541): 8.73e-29: 122: 16.11
+	Mm
		659344 MAX_MOUSE (60-166): 2.79e-12: 64.5: 19.63		WDR5_MOUSE (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		898091 MAX_HUMAN (60-166): 6.51e-12: 63.3: 19.63		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92