HitPredict

Interactor 1: ERF (P50548)
ETS domain-containing transcription factor ERF (Ets2 repressor factor) (PE-2)
Gene: ERF

Interactor 2: Q6FHY5 (Q6FHY5)
MEOX2 protein
Gene: MEOX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 303
+	Hs
		837871 ERF_HUMAN (1-548): 2.67e-75: 250: 100.00		MEOX2_HUMAN (1-303): 9.39e-59: 192: 99.01
+	Hs
		794549 ETV4_HUMAN (1-168): 9.4e-41: 155: 31.77		Q6FHY5_HUMAN (1-303): 1.46e-60: 196: 100.00
+	Hs
		794528 ETV4_HUMAN (1-168): 9.4e-41: 155: 31.77		MEOX2_HUMAN (1-303): 9.39e-59: 192: 99.01
+	Hs
		541983 ETS1_HUMAN (14-131): 5.65e-45: 166: 48.31		PIT1_HUMAN (13-251): 2.93e-31: 120: 17.76
+	Dm
		949985 ELG_DROME (16-145): 1.49e-43: 163: 41.54		UBX_DROME (40-247): 1.77e-31: 122: 25.00
+	Hs
		882119 FLI1_HUMAN (2-204): 5.44e-44: 163: 34.48		GSC_HUMAN (31-269): 9.75e-32: 120: 18.52
+	Ce
		484983 Q400M2_CAEEL (9-136): 1.83e-43: 161: 33.33		MAB5_CAEEL (142-269): 7.69e-31: 116: 31.25
+	Hs
		584241 ELK1_HUMAN (26-452): 5.74e-34: 135: 19.68		EMX1_HUMAN (98-259): 1.26e-38: 139: 31.95
+	Dm
		669754 ETS3_DROME (2-210): 9.65e-39: 150: 34.76		Q9XZU0_DROME (178-299): 7.89e-31: 120: 27.05
+	Ce
		109652 H2KYY1_CAEEL (9-136): 1.61e-40: 153: 33.33		MAB5_CAEEL (142-269): 7.69e-31: 116: 31.25
+	Dm
		669726 ETS3_DROME (2-210): 9.65e-39: 150: 34.76		Q8T0V5_DROME (178-299): 1.45e-30: 119: 27.05
+	Dm
		669733 ETS3_DROME (2-210): 9.65e-39: 150: 34.76		Q9VCY0_DROME (137-253): 7.06e-31: 115: 41.32
+	Dm
		669728 ETS3_DROME (2-210): 9.65e-39: 150: 34.76		Q9U984_DROME (137-253): 7.74e-30: 112: 41.32
+	Hs
		567877 FEV_HUMAN (10-219): 1.19e-36: 138: 33.65		HXB9_HUMAN (36-251): 4e-31: 118: 24.78
+	Hs
		987769 GABPA_HUMAN (2-131): 7.54e-46: 169: 40.00		GBX1_HUMAN (185-255): 1.3e-13: 72.4: 53.52
+	Hs
		785344 ELK3_HUMAN (41-206): 5.54e-43: 160: 30.95		MNX1_HUMAN (179-252): 1.26e-14: 75.5: 54.05
+	Hs
		446866 ETV4_HUMAN (1-168): 9.4e-41: 155: 31.77		HXD4_HUMAN (185-243): 1.43e-15: 76.6: 61.02
+	Hs
		837772 ETV7_HUMAN (7-143): 3.2e-36: 139: 25.36		MNX1_HUMAN (179-252): 1.26e-14: 75.5: 54.05
+	Hs
		837769 FEV_HUMAN (10-219): 1.19e-36: 138: 33.65		MNX1_HUMAN (179-252): 1.26e-14: 75.5: 54.05
+	Hs
		201848 SYNJ1_HUMAN (231-487): 2.78e-12: 71.8: 13.21		HXA2_HUMAN (63-301): 7.31e-30: 118: 20.16