HitPredict

Interactor 1: ETV1 (P50549)
ETS translocation variant 1 (Ets-related protein 81)
Gene: ETV1

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	14747462, 12917345
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 477 Hs			1 2414
+	Hs
		794535 ETV4_HUMAN (3-477): 4.41e-170: 489: 54.10		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Mm
		70899 ETV4_MOUSE (3-477): 4.22e-166: 479: 53.78		EP300_MOUSE (1-2414): 0: 1090: 93.01
+	Hs
		781139 ETV5_HUMAN (1-477): 4.27e-151: 442: 59.42		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		987759 GABPA_HUMAN (76-442): 6.41e-104: 319: 18.59		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		507409 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		542741 ETS2_HUMAN (187-441): 2.68e-67: 224: 25.91		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		840443 ETV1_HUMAN (1-477): 0: 528: 100.00		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		794578 ETV4_HUMAN (3-477): 4.41e-170: 489: 54.10		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		794560 ETV4_HUMAN (3-477): 4.41e-170: 489: 54.10		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Hs
		507535 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		507528 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		507371 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20
+	Hs
		542769 ETS2_HUMAN (187-441): 2.68e-67: 224: 25.91		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		507429 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Mm
		101434 GABPA_MOUSE (76-442): 1.85e-102: 315: 18.34		F8VPR5_MOUSE (1752-2401): 7.8e-10: 67.1: 12.31
+	Hs
		507518 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02
+	Hs
		507468 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13
+	Hs
		507480 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Hs
		965407 FLI1_HUMAN (104-476): 6.04e-85: 270: 21.13		PB1_HUMAN (1081-1145): 9.68e-11: 69.8: 36.92
+	Hs
		542756 ETS2_HUMAN (187-441): 2.68e-67: 224: 25.91		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25