HitPredict

Interactor 1: ETV1 (P50549)
ETS translocation variant 1 (Ets-related protein 81)
Gene: ETV1

Interactor 2: NCOA2 (Q15596)
Nuclear receptor coactivator 2 (NCoA-2) (Class E basic helix-loop-helix protein 75) (bHLHe75) (Transcriptional intermediary factor 2) (hTIF2)
Gene: NCOA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	14747462
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 477 Hs			1 1464
+	Hs
		794543 ETV4_HUMAN (3-477): 4.41e-170: 489: 54.10		NCOA2_HUMAN (1-1464): 0: 616: 100.00
+	Hs
		507434 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		NCOA2_HUMAN (1-1464): 0: 616: 100.00
+	Hs
		840443 ETV1_HUMAN (1-477): 0: 528: 100.00		NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52
+	Hs
		794548 ETV4_HUMAN (3-477): 4.41e-170: 489: 54.10		HIF1A_HUMAN (13-835): 8.2e-109: 366: 13.75
+	Hs
		794578 ETV4_HUMAN (3-477): 4.41e-170: 489: 54.10		NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52
+	Hs
		794562 ETV4_HUMAN (3-477): 4.41e-170: 489: 54.10		EPAS1_HUMAN (13-798): 4.66e-96: 332: 14.47
+	Hs
		1075387 FEV_HUMAN (315-464): 2.08e-49: 170: 38.00		NCOA2_HUMAN (1-1464): 0: 616: 100.00
+	Hs
		507535 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52
+	Hs
		542769 ETS2_HUMAN (187-441): 2.68e-67: 224: 25.91		NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52
+	Hs
		542091 ETS1_HUMAN (180-440): 3.28e-56: 194: 28.16		NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52
+	Hs
		542070 ETS1_HUMAN (180-440): 3.28e-56: 194: 28.16		EPAS1_HUMAN (13-798): 4.66e-96: 332: 14.47
+	Hs
		584252 ELK1_HUMAN (334-473): 1.19e-43: 160: 38.19		HIF1A_HUMAN (13-835): 8.2e-109: 366: 13.75
+	Hs
		542745 ETS2_HUMAN (187-441): 2.68e-67: 224: 25.91		NCOA1_HUMAN (1-1460): 8.21e-80: 292: 28.32
+	Hs
		1304733 FEV_HUMAN (315-464): 2.08e-49: 170: 38.00		NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52
+	Hs
		584271 ELK1_HUMAN (334-473): 1.19e-43: 160: 38.19		EPAS1_HUMAN (13-798): 4.66e-96: 332: 14.47
+	Hs
		542016 ETS1_HUMAN (180-440): 3.28e-56: 194: 28.16		NCOA1_HUMAN (1-1460): 8.21e-80: 292: 28.32
+	Hs
		649147 FEV_HUMAN (315-464): 2.08e-49: 170: 38.00		ARNT_HUMAN (4-664): 7.44e-75: 268: 14.99
+	Hs
		507468 ERG_HUMAN (101-476): 5.19e-95: 297: 20.31		KMT2C_HUMAN (670-1422): 5e-11: 70.1: 13.05
+	Hs
		1243851 ELF5_HUMAN (171-414): 2.6e-67: 218: 21.71		KMT2C_HUMAN (670-1422): 5e-11: 70.1: 13.05
+	Hs
		1243834 FEV_HUMAN (315-464): 2.08e-49: 170: 38.00		KMT2C_HUMAN (670-1422): 5e-11: 70.1: 13.05