HitPredict

Interactor 1: VASP (P50552)
Vasodilator-stimulated phosphoprotein (VASP)
Gene: VASP

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 375
+	Hs
		1122440 HOME1_HUMAN (1-182): 5.61e-51: 175: 23.24		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		840454 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		840455 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		357 A0A075B6E5_HUMAN (1-159): 1.64e-69: 219: 52.20		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		358 A0A075B6E5_HUMAN (1-159): 1.64e-69: 219: 52.20		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		930044 EVL_HUMAN (1-375): 2.06e-60: 202: 43.68		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		891877 HOME1_HUMAN (1-182): 5.61e-51: 175: 23.24		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		891898 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929926 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932262 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		ACTC_HUMAN (2-375): 0: 592: 94.12