HitPredict

Interactor 1: VASP (P50552)
Vasodilator-stimulated phosphoprotein (VASP)
Gene: VASP

Interactor 2: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0030036 - actin cytoskeleton organization GO:0045296 - cadherin binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 1748
+	Hs
		1232508 HOME2_HUMAN (1-162): 1.41e-59: 198: 23.64		PALS1_HUMAN (272-806): 1.75e-82: 288: 15.67
+	Hs
		1205706 HOME1_HUMAN (1-182): 5.61e-51: 175: 23.24		PALS1_HUMAN (272-806): 1.75e-82: 288: 15.67
+	Hs
		1232509 HOME3_HUMAN (3-294): 6.76e-48: 168: 18.54		PALS1_HUMAN (272-806): 1.75e-82: 288: 15.67
+	Hs
		840531 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		INADL_HUMAN (60-583): 5.65e-19: 96.5: 18.77
+	Hs
		280038 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		MPDZ_HUMAN (31-489): 8.85e-18: 92.6: 13.61
+	Hs
		840597 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98
+	Mm
		1143536 HOME2_MOUSE (1-162): 5.14e-59: 196: 23.64		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Mm
		1143478 HOME3_MOUSE (3-294): 4.06e-54: 184: 17.85		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Hs
		1246441 HOME2_HUMAN (1-162): 1.41e-59: 198: 23.64		INADL_HUMAN (60-583): 5.65e-19: 96.5: 18.77
+	Mm
		1143567 HOME1_MOUSE (1-182): 1.37e-49: 172: 23.78		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Hs
		1205710 HOME1_HUMAN (1-182): 5.61e-51: 175: 23.24		INADL_HUMAN (60-583): 5.65e-19: 96.5: 18.77
+	Hs
		1246442 HOME3_HUMAN (3-294): 6.76e-48: 168: 18.54		INADL_HUMAN (60-583): 5.65e-19: 96.5: 18.77
+	Mm
		1143531 MINK1_MOUSE (88-364): 1.96e-21: 98.6: 13.62		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Mm
		975399 ENAH_MOUSE (109-379): 3.12e-16: 82.4: 28.17		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Dm
		113976 M9PB30_DROME (83-341): 6.46e-09: 60: 11.89		M9PB30_DROME (1108-1664): 5.31e-24: 113: 15.83