HitPredict

Interactor 1: VASP (P50552)
Vasodilator-stimulated phosphoprotein (VASP)
Gene: VASP

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.713

Property	Details
Experiments	26186194, 28514442, 32296183, 34079125, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008154 - actin polymerization or depolymerization GO:0017124 - SH3 domain binding GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 508
+	Hs
		1205704 HOME1_HUMAN (1-182): 5.61e-51: 175: 23.24		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		840586 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		1224647 HOME3_HUMAN (3-294): 6.76e-48: 168: 18.54		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		1224613 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Mm
		1208103 MINK1_MOUSE (88-364): 1.96e-21: 98.6: 13.62		ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93
+	Hs
		203214 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		SYNJ1_HUMAN (38-463): 1.36e-41: 161: 11.55
+	Hs
		1345510 HOME3_HUMAN (3-294): 6.76e-48: 168: 18.54		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Mm
		936832 VASP_MOUSE (1-380): 3.09e-96: 293: 87.63		LASP1_MOUSE (285-503): 1.88e-32: 126: 19.73
+	Dm
		1250361 ENA_DROME (2-235): 1.21e-41: 158: 36.33		Q9Y0S9_DROME (1-504): 2.01e-77: 252: 34.72
+	Hs
		840475 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Hs
		166036 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		SYNJ2_HUMAN (39-458): 2.1e-26: 115: 13.88
+	Hs
		1237890 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		840593 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		ABI3_HUMAN (250-502): 1.37e-16: 83.3: 25.48
+	Hs
		1350201 EVL_HUMAN (1-375): 2.06e-60: 202: 43.68		ABI3_HUMAN (250-502): 1.37e-16: 83.3: 25.48
+	Hs
		1345493 HOME2_HUMAN (1-162): 1.41e-59: 198: 23.64		ABI3_HUMAN (250-502): 1.37e-16: 83.3: 25.48
+	Hs
		1191864 EVL_HUMAN (1-375): 2.06e-60: 202: 43.68		SH3R1_HUMAN (244-503): 3.15e-09: 61.6: 17.28
+	Hs
		1205738 HOME1_HUMAN (1-182): 5.61e-51: 175: 23.24		DBNL_HUMAN (316-503): 2.32e-17: 86.1: 20.53
+	Hs
		1205736 HOME1_HUMAN (1-182): 5.61e-51: 175: 23.24		ABI3_HUMAN (250-502): 1.37e-16: 83.3: 25.48
+	Hs
		1345512 HOME3_HUMAN (3-294): 6.76e-48: 168: 18.54		ABI3_HUMAN (250-502): 1.37e-16: 83.3: 25.48
+	Hs
		1237895 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		ABI3_HUMAN (250-502): 1.37e-16: 83.3: 25.48