HitPredict

Interactor 1: VASP (P50552)
Vasodilator-stimulated phosphoprotein (VASP)
Gene: VASP

Interactor 2: SRBS1 (Q9BX66)
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
Gene: SORBS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 1292
+	Hs
		360628 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		SPTA1_HUMAN (303-1028): 9.45e-45: 180: 9.89
+	Hs
		209012 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		NCK2_HUMAN (767-1019): 1.85e-42: 162: 16.23
+	Hs
		1045559 EVL_HUMAN (1-375): 2.06e-60: 202: 43.68		SPTN1_HUMAN (304-902): 8.17e-59: 225: 13.39
+	Mm
		82779 HOME1_MOUSE (1-182): 1.37e-49: 172: 23.78		B9EKJ1_MOUSE (304-921): 5.86e-58: 223: 13.46
+	Mm
		561177 HOME1_MOUSE (1-182): 1.37e-49: 172: 23.78		SPTN1_MOUSE (304-921): 8.47e-58: 222: 13.46
+	Hs
		360670 EVL_HUMAN (1-375): 2.06e-60: 202: 43.68		SPTA1_HUMAN (303-1028): 9.45e-45: 180: 9.89
+	Hs
		840508 VASP_HUMAN (1-380): 1.43e-91: 281: 100.00		DNMBP_HUMAN (796-1253): 2.23e-17: 90.7: 14.23
+	Hs
		297982 HOME1_HUMAN (1-182): 5.61e-51: 175: 23.24		FCSD2_HUMAN (340-994): 3.64e-50: 192: 11.44
+	Hs
		557740 MINK1_HUMAN (88-364): 7.5e-36: 141: 15.90		NCK1_HUMAN (708-1005): 1.37e-49: 182: 18.27
+	Hs
		209112 MINK1_HUMAN (88-364): 7.5e-36: 141: 15.90		NCK2_HUMAN (767-1019): 1.85e-42: 162: 16.23
+	Ce
		104681 G5EG53_CAEEL (2-369): 1.91e-66: 219: 19.87		SRBS1_CAEEL (268-848): 2.47e-13: 77.3: 17.04
+	Hs
		1167834 EVL_HUMAN (1-375): 2.06e-60: 202: 43.68		DNMBP_HUMAN (796-1253): 2.23e-17: 90.7: 14.23
+	Hs
		360652 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		SPTA1_HUMAN (303-1028): 9.45e-45: 180: 9.89
+	Hs
		1191864 EVL_HUMAN (1-375): 2.06e-60: 202: 43.68		SH3R1_HUMAN (220-850): 8.23e-10: 65.6: 13.22
+	Hs
		1167839 DYN3_HUMAN (15-212): 2.77e-38: 148: 20.98		DNMBP_HUMAN (796-1253): 2.23e-17: 90.7: 14.23
+	Hs
		1167809 ENAH_HUMAN (109-379): 3.91e-23: 102: 30.06		DNMBP_HUMAN (796-1253): 2.23e-17: 90.7: 14.23
+	Dm
		113976 M9PB30_DROME (83-341): 6.46e-09: 60: 11.89		M9PB30_DROME (21-776): 2.85e-13: 77.4: 10.64