HitPredict

Interactor 1: ASCL1 (P50553)
Achaete-scute homolog 1 (ASH-1) (hASH1) (Class A basic helix-loop-helix protein 46) (bHLHa46)
Gene: ASCL1

Interactor 2: MEF2A (Q02078)
Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1)
Gene: MEF2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.625

The method score is based on:

Property Details
Experiments 8662987, 8900141
Identification Methods pull down, affinity chromatography technology, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 5 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 236
Hs

1 507
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024