Interactor 1: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 28514442, 27107012, 31980649, 33961781, 11746524, 19380743, 21706016, 15834155, 16696976, 21988832, unassigned2173
Identification Methods affinity chromatography technology, two hybrid, pull down, barcode fusion genetics two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, validated two hybrid, surface plasmon resonance
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~SH3_1
Common GO terms GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 870
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024