HitPredict

Interactor 1: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Interactor 2: FCSD1 (Q86WN1)
F-BAR and double SH3 domains protein 1 (Protein nervous wreck 2) (NWK2)
Gene: FCHSD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19041431
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_9
Common GO terms	GO:0055037 - recycling endosome GO:0061024 - membrane organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 870 Hs			1 690
+	Hs
		840723 DYN2_HUMAN (1-870): 0: 1057: 100.00		FBP1L_HUMAN (14-613): 5.33e-60: 214: 12.92
+	Hs
		983392 DYN1_HUMAN (1-846): 0: 1002: 79.04		NOSTN_HUMAN (22-536): 4.93e-81: 268: 15.93
+	Hs
		840798 DYN2_HUMAN (1-870): 0: 1057: 100.00		FNBP1_HUMAN (14-614): 3.84e-51: 189: 13.31
+	Hs
		840700 DYN2_HUMAN (1-870): 0: 1057: 100.00		CIP4_HUMAN (13-606): 2.88e-48: 181: 12.99
+	Hs
		983403 DYN1_HUMAN (1-846): 0: 1002: 79.04		FNBP1_HUMAN (14-614): 3.84e-51: 189: 13.31
+	Hs
		1301542 DYN3_HUMAN (1-870): 0: 994: 78.41		FNBP1_HUMAN (14-614): 3.84e-51: 189: 13.31
+	Hs
		840840 DYN2_HUMAN (1-870): 0: 1057: 100.00		ITSN2_HUMAN (145-685): 2.17e-22: 105: 10.72
+	Hs
		840702 DYN2_HUMAN (1-870): 0: 1057: 100.00		ITSN1_HUMAN (12-631): 3.75e-22: 104: 11.96
+	Mm
		760488 DYN2_MOUSE (1-870): 0: 1057: 98.16		ITSN1_MOUSE (380-631): 7.67e-21: 100: 15.63
+	Mm
		760487 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN2_MOUSE (260-608): 3.41e-18: 90.3: 14.62
+	Mm
		760485 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN3_MOUSE (310-605): 7.93e-14: 76.2: 16.83
+	Hs
		840860 DYN2_HUMAN (1-870): 0: 1057: 100.00		PACN3_HUMAN (310-605): 1.18e-13: 75.5: 18.77
+	Dm
		112674 DYN_DROME (6-842): 0: 928: 66.23		M9NE16_DROME (14-606): 2.52e-50: 187: 13.75
+	Hs
		983379 DYN1_HUMAN (1-846): 0: 1002: 79.04		ITSN1_HUMAN (12-631): 3.75e-22: 104: 11.96
+	Mm
		760469 DYN1_MOUSE (1-844): 0: 1003: 79.23		ITSN1_MOUSE (380-631): 7.67e-21: 100: 15.63
+	Rn
		599413 DYN1_RAT (1-846): 0: 994: 78.57		ITSN1_RAT (380-631): 4.3e-21: 101: 15.23
+	Dm
		112570 DYN_DROME (6-842): 0: 928: 66.23		M9ND00_DROME (389-615): 2.24e-37: 152: 20.80
+	Hs
		983416 DYN1_HUMAN (1-846): 0: 1002: 79.04		PACN3_HUMAN (310-605): 1.18e-13: 75.5: 18.77
+	Mm
		223006 DYN1_MOUSE (1-844): 0: 1003: 79.23		NCK2_MOUSE (418-627): 3.71e-13: 73.7: 24.78
+	Hs
		557664 DYN1_HUMAN (1-846): 0: 1002: 79.04		NCK1_HUMAN (477-618): 2.4e-13: 74.1: 26.47