HitPredict

Interactor 1: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	10542231
Identification Methods	peptide array
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0002102 - podosome GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0098793 - presynapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 870 Hs			1 368
+	Hs
		840808 DYN2_HUMAN (1-870): 0: 1057: 100.00		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		840807 DYN2_HUMAN (1-870): 0: 1057: 100.00		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Mm
		760453 DYN1_MOUSE (1-844): 0: 1003: 79.23		SH3G1_MOUSE (1-368): 7.42e-89: 273: 94.02
+	Mm
		760455 DYN1_MOUSE (1-844): 0: 1003: 79.23		SH3G3_MOUSE (1-367): 8.72e-87: 267: 63.76
+	Mm
		760454 DYN1_MOUSE (1-844): 0: 1003: 79.23		SH3G2_MOUSE (1-368): 8.98e-84: 260: 69.02
+	Mm
		760467 DYN1_MOUSE (1-844): 0: 1003: 79.23		SHLB1_MOUSE (10-363): 3.6e-69: 223: 25.00
+	Mm
		760473 DYN2_MOUSE (1-870): 0: 1057: 98.16		SRC8_MOUSE (85-362): 7.3e-38: 144: 13.62
+	Hs
		840692 DYN2_HUMAN (1-870): 0: 1057: 100.00		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		840812 DYN2_HUMAN (1-870): 0: 1057: 100.00		PACN1_HUMAN (16-363): 9.35e-37: 139: 14.89
+	Hs
		207784 DYN2_HUMAN (1-870): 0: 1057: 100.00		PPIP1_HUMAN (13-363): 1.87e-36: 138: 15.87
+	Mm
		760475 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN1_MOUSE (16-363): 2.86e-35: 135: 14.61
+	Mm
		760487 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN2_MOUSE (16-364): 5.31e-35: 135: 14.71
+	Hs
		840864 DYN2_HUMAN (1-870): 0: 1057: 100.00		PACN2_HUMAN (16-364): 1.92e-34: 134: 14.97
+	Mm
		760451 DYN1_MOUSE (1-844): 0: 1003: 79.23		PACN1_MOUSE (16-363): 2.86e-35: 135: 14.61
+	Hs
		840811 DYN2_HUMAN (1-870): 0: 1057: 100.00		SRBS1_HUMAN (235-363): 3.59e-15: 79.2: 25.95
+	Hs
		840747 DYN2_HUMAN (1-870): 0: 1057: 100.00		SH3R1_HUMAN (305-361): 9.5e-13: 71.7: 49.18
+	Rn
		192740 DYN2_RAT (1-870): 0: 1053: 98.05		SRBS2_RAT (264-363): 2.11e-12: 70.5: 22.55
+	Mm
		760474 DYN2_MOUSE (1-870): 0: 1057: 98.16		GRB2_MOUSE (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		840663 DYN2_HUMAN (1-870): 0: 1057: 100.00		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Mm
		760450 DYN1_MOUSE (1-844): 0: 1003: 79.23		GRB2_MOUSE (311-367): 1.59e-11: 65.2: 41.38