Interactor 1: TNF10 (P50591)
Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)
Gene: TNFSF10

Interactor 2: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.759

The method score is based on:

Property Details
Experiments 25551360, 19432816, 16554480, 22266862, 22585859, 21822306, 16801533, 10894161, 16227629, 19427028, 12198154, 10894160, 20097879, 21525171, 21459798, 23678861
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005164 - tumor necrosis factor receptor binding
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0043065 - positive regulation of apoptotic process
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 281
Hs

1 208
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024