Interactor 1: TNF10 (P50591)
Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)
Gene: TNFSF10
Interactor 2: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.95 | 0.60 | 0.759 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25551360, 19432816, 16554480, 22266862, 22585859, 21822306, 16801533, 10894161, 16227629, 19427028, 12198154, 10894160, 20097879, 21525171, 21459798, 23678861 |
Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation, pull down |
Interaction Type | physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005164 - tumor necrosis factor receptor binding GO:0005886 - plasma membrane GO:0006915 - apoptotic process GO:0043065 - positive regulation of apoptotic process GO:0043123 - positive regulation of canonical NF-kappaB signal transduction and 1 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024