Interactor 1: TNF10 (P50591)
Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)
Gene: TNFSF10

Interactor 2: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 19432816, 22585859
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0043065 - positive regulation of apoptotic process
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:2001238 - positive regulation of extrinsic apoptotic signaling pathway
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 281
Hs

1 671
+ Hs
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024