HitPredict

Interactor 1: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Interactor 2: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 29568061, 36042349, 10082552, 11113184, 9315650, 10993082, 23602568
Identification Methods affinity chromatography technology, proximity labelling technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000439 - transcription factor TFIIH core complex
GO:0001650 - fibrillar center
GO:0001673 - male germ cell nucleus
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
and 26 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 346
Hs

1 346
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024