HitPredict

Interactor 1: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Interactor 2: TXTP (P53007)
Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Mitochondrial citrate carrier) (CIC) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)
Gene: SLC25A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36042349
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 311
+	Hs
		518087 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		ADT1_HUMAN (115-309): 1.18e-35: 131: 22.22
+	Hs
		397321 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67
+	Hs
		518108 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		ADT1_HUMAN (115-309): 1.18e-35: 131: 22.22
+	Hs
		518292 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		ADT3_HUMAN (121-310): 2.98e-35: 131: 22.28
+	Hs
		841306 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		ODC_HUMAN (27-308): 2.31e-29: 115: 28.90
+	Hs
		841325 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		GHC1_HUMAN (21-297): 1.35e-25: 105: 27.42
+	Hs
		397227 CDK1_HUMAN (9-298): 6.62e-135: 387: 43.00		ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67
+	Mm
		509475 CDK1_MOUSE (9-298): 3.17e-133: 383: 43.35		ADT2_MOUSE (116-310): 6.91e-36: 132: 23.19
+	Hs
		841231 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		KMCP1_HUMAN (221-307): 1.93e-16: 79.9: 26.32