Interactor 1: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Interactor 2: TF2H2 (Q13888)
General transcription factor IIH subunit 2 (Basic transcription factor 2 44 kDa subunit) (BTF2 p44) (General transcription factor IIH polypeptide 2) (TFIIH basal transcription factor complex p44 subunit)
Gene: GTF2H2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 11062469, 10924514, 28977422, 29568061, 35271311, 32707033, 36736316, 17643375, 23602568, 19934020, unassigned1655
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000439 - transcription factor TFIIH core complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005675 - transcription factor TFIIH holo complex
GO:0006366 - transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 346
Hs

1 395
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024