Interactor 1: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Interactor 2: TF2H5 (Q6ZYL4)
General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) (TFIIH subunit p8)
Gene: GTF2H5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.55 0.719

The method score is based on:

Property Details
Experiments 26496610, 15220921, 29568061, 35271311, 32707033, 36736316, 23602568, unassigned1655
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000439 - transcription factor TFIIH core complex
GO:0005654 - nucleoplasm
GO:0005675 - transcription factor TFIIH holo complex
GO:0005737 - cytoplasm
GO:0006366 - transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024