HitPredict

Interactor 1: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Interactor 2: RB6I2 (Q8IUD2)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)
Gene: ERC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 1116
+	Hs
		625176 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		724717 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		522542 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		MYH1_HUMAN (390-1116): 2.17e-34: 146: 13.62
+	Hs
		960129 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		MYH13_HUMAN (1-745): 5.53e-31: 134: 9.88
+	Hs
		1216120 CDK20_HUMAN (11-310): 1.24e-77: 243: 43.28		RB6I2_HUMAN (1-1116): 2.23e-82: 293: 100.00
+	Hs
		528401 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		MYH8_HUMAN (3-541): 4.07e-23: 109: 10.26
+	Hs
		625177 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		MYH10_HUMAN (664-1113): 2.61e-18: 93.3: 12.09
+	Hs
		528368 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		MYH6_HUMAN (3-544): 6.64e-24: 111: 9.47
+	Hs
		960128 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		MYH2_HUMAN (3-612): 1.73e-23: 110: 9.34
+	Hs
		528405 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		MYH8_HUMAN (3-541): 4.07e-23: 109: 10.26
+	Hs
		725114 CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00		MYH10_HUMAN (664-1113): 2.61e-18: 93.3: 12.09
+	Hs
		522604 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		MYH7_HUMAN (6-513): 7.72e-21: 101: 9.84
+	Hs
		502908 CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85		MYH3_HUMAN (4-532): 1.56e-20: 100: 10.40
+	Hs
		551610 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		DESP_HUMAN (457-1104): 2.2e-09: 64.3: 13.22
+	Hs
		625530 CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85		MY18A_HUMAN (439-976): 3.58e-09: 63.5: 18.73
+	Hs
		148286 CDK1_HUMAN (9-298): 6.62e-135: 387: 43.00		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Hs
		414713 CDK1_HUMAN (9-298): 6.62e-135: 387: 43.00		DESP_HUMAN (457-1104): 2.2e-09: 64.3: 13.22