Interactor 1: UBC9 (P50623)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC9

Interactor 2: SIZ1 (Q04195)
E3 SUMO-protein ligase SIZ1 (EC 2.3.2.-) (E3 SUMO-protein transferase SIZ2) (SAP and Miz-finger domain-containing protein 1) (Ubiquitin-like protein ligase 1)
Gene: SIZ1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 11587849, 11572779, 16109721, 23571759, 16204216, 24753409, 23443663, 22705796, 11577116, 26083678, 27509863, 19748360
Identification Methods coimmunoprecipitation, pull down, affinity chromatography technology, two hybrid, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PINIT~UQ_con, UQ_con~zf-MIZ
Common GO terms GO:0005634 - nucleus
GO:0016925 - protein sumoylation
GO:0019789 - SUMO transferase activity
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 157
Sc

1 904
+ At
+ Sc
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Dm
+ Hs
+ Mm
+ At
+ Dm
+ Ce

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Last updated: 15 Jul 2024