HitPredict

Interactor 1: UBC9 (P50623)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC9

Interactor 2: RHC31 (Q06624)
DNA damage tolerance protein RHC31 (RAD31 homolog)
Gene: AOS1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.845

Property	Details
Experiments	15738391, 26633173, 21209884
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~UQ_con
Common GO terms	GO:0005634 - nucleus GO:0016925 - protein sumoylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 157 Sc			1 347
+	Hs
		930427 UBC9_HUMAN (1-156): 5.53e-69: 207: 56.41		SAE1_HUMAN (5-347): 8.36e-108: 320: 32.29
+	At
		1114935 SCE1_ARATH (2-155): 7.8e-73: 216: 59.74		SAE1A_ARATH (3-347): 4.37e-91: 277: 24.72
+	Hs
		919796 UB2D2_HUMAN (4-156): 2.79e-73: 217: 32.68		UBA3_HUMAN (25-341): 6.24e-84: 263: 17.83
+	Dm
		1181392 Q7KNM2_DROME (1-156): 5.99e-73: 217: 53.85		Q7KSM5_DROME (1-342): 3.07e-74: 234: 28.98
+	Hs
		48104 UB2D1_HUMAN (4-156): 1.54e-73: 218: 33.99		UBA6_HUMAN (14-204): 3.3e-47: 173: 16.34
+	Hs
		48107 UB2D2_HUMAN (4-156): 2.79e-73: 217: 32.68		UBA6_HUMAN (14-204): 3.3e-47: 173: 16.34
+	Hs
		48106 UB2D3_HUMAN (4-156): 3.32e-72: 215: 32.68		UBA6_HUMAN (14-204): 3.3e-47: 173: 16.34
+	Sc
		608711 UBC9_YEAST (1-157): 4.84e-76: 225: 100.00		UBA1_YEAST (4-283): 7.77e-44: 163: 15.89
+	Hs
		607190 UB2D4_HUMAN (4-156): 2.62e-74: 220: 33.33		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	Hs
		607026 UB2D1_HUMAN (4-156): 1.54e-73: 218: 33.99		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	Hs
		607050 UB2D2_HUMAN (4-156): 2.79e-73: 217: 32.68		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	Sc
		549788 UBC4_YEAST (1-156): 3.15e-72: 215: 33.33		UBA1_YEAST (4-283): 7.77e-44: 163: 15.89
+	Hs
		607039 UB2D3_HUMAN (4-156): 3.32e-72: 215: 32.68		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	Sp
		293848 UBC4_SCHPO (4-156): 3.4e-72: 215: 33.33		UBA1_SCHPO (15-257): 1.6e-41: 156: 17.44
+	Hs
		607055 UBC9_HUMAN (1-156): 5.53e-69: 207: 56.41		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	Hs
		607136 UB2E2_HUMAN (3-156): 4.04e-68: 206: 31.17		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	Hs
		607129 UB2E3_HUMAN (3-156): 1.16e-67: 205: 31.17		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	Hs
		607023 UBE2A_HUMAN (1-154): 1.04e-66: 201: 38.96		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	Hs
		607028 UB2E1_HUMAN (3-156): 3.29e-66: 201: 31.82		UBA1_HUMAN (4-304): 9.94e-44: 162: 18.04
+	At
		1115004 SCE1_ARATH (2-155): 7.8e-73: 216: 59.74		SAE2_ARATH (28-166): 1.77e-12: 70.5: 28.37