HitPredict

Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 15328539, 10958691, 18971272, 20603019, 14580347, 18566585, 11572868, 21729782, 8870681, 9557739, 9491887, 23602568
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001223 - transcription coactivator binding
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0004672 - protein kinase activity
and 36 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 372
Hs

1 372
+ Hs
+ Hs
+ Rn
+ At
+ Hs
+ At
+ At
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Zm
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024