Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Interactor 2: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 24189400, 24981860, 33961781, 26186194, 28514442, 27684187, 35271311, 32707033, 20305087, 23455922, 25036637
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, pull down, luminescence based mammalian interactome mapping
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~Pkinase, CDC37_N~Pkinase
Common GO terms GO:0019901 - protein kinase binding
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 372
Hs

1 378
+ Mm
+ Hs
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Ce
+ Sc
+ Ca

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Last updated: 15 Jul 2024