Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9
Interactor 2: AFF4 (Q9UHB7)
AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein)
Gene: AFF4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 12065898, 33961781, 20153263, 21873227, 21729782, 27684187, 32479599, 32707033, 36736316, 17643375, 22483617, 23602568, 23455922 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AF-4~Pkinase |
| Common GO terms | GO:0005654 - nucleoplasm GO:0008023 - transcription elongation factor complex |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
