HitPredict

Interactor 1: LRBA (P50851)
Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) (CDC4-like protein)
Gene: LRBA

Interactor 2: NTRK2 (Q16620)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)
Gene: NTRK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2863 Hs			1 822
+	Hs
		841979 LRBA_HUMAN (1-2863): 0: 3610: 100.00		NTRK3_HUMAN (13-822): 1.98e-178: 536: 52.84
+	Hs
		607923 LRBA_HUMAN (1-2863): 0: 3610: 100.00		FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68
+	Hs
		384506 LRBA_HUMAN (1-2863): 0: 3610: 100.00		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		507915 LRBA_HUMAN (1-2863): 0: 3610: 100.00		FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77
+	Hs
		842042 LRBA_HUMAN (1-2863): 0: 3610: 100.00		ALK_HUMAN (513-799): 4.96e-64: 236: 41.44
+	Hs
		1081538 NBEA_HUMAN (35-2863): 0: 2968: 62.96		NTRK3_HUMAN (13-822): 1.98e-178: 536: 52.84
+	Hs
		608051 NBEA_HUMAN (35-2863): 0: 2968: 62.96		FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68
+	Hs
		385193 NBEA_HUMAN (35-2863): 0: 2968: 62.96		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		508110 NBEA_HUMAN (35-2863): 0: 2968: 62.96		FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77
+	Hs
		1244931 NBEA_HUMAN (35-2863): 0: 2968: 62.96		ALK_HUMAN (513-799): 4.96e-64: 236: 41.44
+	Hs
		666623 NBEA_HUMAN (35-2863): 0: 2968: 62.96		LTK_HUMAN (506-808): 6.29e-61: 223: 38.07
+	Hs
		921579 GBB2_HUMAN (2606-2859): 1.83e-37: 147: 14.29		NTRK3_HUMAN (13-822): 1.98e-178: 536: 52.84
+	Hs
		609202 LIS1_HUMAN (2724-2862): 1.62e-38: 152: 9.93		FGFR3_HUMAN (128-822): 1.4e-170: 514: 24.45
+	Hs
		384438 LIS1_HUMAN (2724-2862): 1.62e-38: 152: 9.93		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		384596 WDR5_HUMAN (2442-2670): 4.14e-32: 131: 11.02		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		384954 WDR81_HUMAN (2631-2861): 3.98e-24: 114: 17.70		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		385045 WDFY4_HUMAN (2727-2861): 1.36e-14: 83: 14.48		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		665199 GBB2_HUMAN (2606-2859): 1.83e-37: 147: 14.29		EPHA2_HUMAN (148-822): 4.29e-141: 443: 22.43