HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 24981860, 35271311, 37071682, 33961781, 35235311
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005832 - chaperonin-containing T-complex
GO:0005874 - microtubule
and 14 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 548
Hs

1 543
+ Bt
+ Mm
+ Bt
+ Hs
+ Bt
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Bt
+ Hs
+ Hs
+ Bt
+ Bt
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024