HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: STK24 (Q9Y6E0)
Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]
Gene: STK24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	18782753
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045296 - cadherin binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 443
+	Hs
		1306764 TCPH_HUMAN (9-538): 0: 564: 26.39		STK24_HUMAN (1-443): 6.47e-163: 468: 100.00
+	Hs
		826963 TCPG_HUMAN (10-547): 0: 558: 28.21		STK24_HUMAN (1-443): 6.47e-163: 468: 100.00
+	Hs
		681746 TCPQ_HUMAN (1-548): 0: 616: 100.00		AKT1_HUMAN (1-357): 1.55e-134: 397: 24.32
+	Hs
		821480 TCPE_HUMAN (2-524): 0: 535: 29.62		STK24_HUMAN (1-443): 6.47e-163: 468: 100.00
+	Hs
		842845 TCPQ_HUMAN (1-548): 0: 616: 100.00		STK4_HUMAN (27-315): 5.08e-129: 383: 52.22
+	Hs
		568592 TCPQ_HUMAN (1-548): 0: 616: 100.00		KAPCA_HUMAN (14-340): 1.26e-129: 379: 23.88
+	Hs
		681999 TCPH_HUMAN (9-538): 0: 564: 26.39		AKT1_HUMAN (1-357): 1.55e-134: 397: 24.32
+	Hs
		1306717 TCPH_HUMAN (9-538): 0: 564: 26.39		STK26_HUMAN (12-439): 6.21e-135: 395: 67.76
+	Hs
		681738 TCPG_HUMAN (10-547): 0: 558: 28.21		AKT1_HUMAN (1-357): 1.55e-134: 397: 24.32
+	Dm
		1179613 Q7K3J0_DROME (1-544): 0: 553: 61.65		AKT1_DROME (25-351): 6.25e-133: 397: 26.27
+	Hs
		1023098 TCPH_HUMAN (9-538): 0: 564: 26.39		STK4_HUMAN (27-315): 5.08e-129: 383: 52.22
+	Hs
		826636 TCPG_HUMAN (10-547): 0: 558: 28.21		STK4_HUMAN (27-315): 5.08e-129: 383: 52.22
+	Hs
		681735 TCPE_HUMAN (2-524): 0: 535: 29.62		AKT1_HUMAN (1-357): 1.55e-134: 397: 24.32
+	Hs
		681747 TCPD_HUMAN (19-525): 0: 530: 28.24		AKT1_HUMAN (1-357): 1.55e-134: 397: 24.32
+	Hs
		568585 TCPE_HUMAN (2-524): 0: 535: 29.62		KAPCA_HUMAN (14-340): 1.26e-129: 379: 23.88
+	Hs
		568593 TCPD_HUMAN (19-525): 0: 530: 28.24		KAPCA_HUMAN (14-340): 1.26e-129: 379: 23.88
+	Hs
		842984 TCPQ_HUMAN (1-548): 0: 616: 100.00		M4K1_HUMAN (31-286): 4.72e-71: 241: 45.08
+	Hs
		1272891 TCPH_HUMAN (9-538): 0: 564: 26.39		M4K1_HUMAN (31-286): 4.72e-71: 241: 45.08
+	Hs
		826805 TCPG_HUMAN (10-547): 0: 558: 28.21		M4K1_HUMAN (31-286): 4.72e-71: 241: 45.08
+	Hs
		821345 TCPE_HUMAN (2-524): 0: 535: 29.62		M4K1_HUMAN (31-286): 4.72e-71: 241: 45.08