HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27705803, 33022573, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Hs			1 334
+	Hs
		826601 TCPG_HUMAN (12-537): 0: 553: 33.40		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		903467 TCPH_HUMAN (12-538): 0: 549: 32.34		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		843299 TCPD_HUMAN (1-539): 0: 602: 100.00		POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89
+	Hs
		843361 TCPD_HUMAN (1-539): 0: 602: 100.00		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		792942 TCPG_HUMAN (12-537): 0: 553: 33.40		LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49
+	Hs
		826784 TCPG_HUMAN (12-537): 0: 553: 33.40		POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89
+	Hs
		826854 TCPG_HUMAN (12-537): 0: 553: 33.40		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		1306650 TCPH_HUMAN (12-538): 0: 549: 32.34		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		843273 TCPD_HUMAN (1-539): 0: 602: 100.00		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		826748 TCPG_HUMAN (12-537): 0: 553: 33.40		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		843219 TCPD_HUMAN (1-539): 0: 602: 100.00		SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71
+	Hs
		1202777 TCPH_HUMAN (12-538): 0: 549: 32.34		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		843411 TCPD_HUMAN (1-539): 0: 602: 100.00		NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54
+	Hs
		843289 TCPD_HUMAN (1-539): 0: 602: 100.00		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		826807 TCPG_HUMAN (12-537): 0: 553: 33.40		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		196979 TCPD_HUMAN (1-539): 0: 602: 100.00		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39
+	Hs
		826772 TCPG_HUMAN (12-537): 0: 553: 33.40		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		1240450 TCPH_HUMAN (12-538): 0: 549: 32.34		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		196973 TCPG_HUMAN (12-537): 0: 553: 33.40		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39
+	Hs
		197078 TCPH_HUMAN (12-538): 0: 549: 32.34		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39