HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	26496610, 18782753, 35271311, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Hs			1 309
+	Hs
		843141 TCPD_HUMAN (1-539): 0: 602: 100.00		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		843130 TCPD_HUMAN (1-539): 0: 602: 100.00		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Sc
		618773 TCPD_YEAST (22-539): 0: 570: 59.20		PP2A1_YEAST (10-309): 0: 517: 76.00
+	Hs
		826610 TCPG_HUMAN (12-537): 0: 553: 33.40		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		826603 TCPG_HUMAN (12-537): 0: 553: 33.40		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		930969 TCPH_HUMAN (12-538): 0: 549: 32.34		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		915267 TCPH_HUMAN (12-538): 0: 549: 32.34		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		821161 TCPE_HUMAN (13-535): 0: 540: 37.88		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		821154 TCPE_HUMAN (13-535): 0: 540: 37.88		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		826591 TCPG_HUMAN (12-537): 0: 553: 33.40		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		890997 TCPH_HUMAN (12-538): 0: 549: 32.34		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		821143 TCPE_HUMAN (13-535): 0: 540: 37.88		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Sc
		618772 TCPG_YEAST (16-537): 0: 527: 31.77		PP2A1_YEAST (10-309): 0: 517: 76.00
+	Sc
		618781 TCPH_YEAST (10-539): 0: 527: 30.73		PP2A1_YEAST (10-309): 0: 517: 76.00
+	Sc
		618836 TCPG_YEAST (16-537): 0: 527: 31.77		PP2A2_YEAST (10-309): 0: 514: 76.67
+	Sc
		618845 TCPH_YEAST (10-539): 0: 527: 30.73		PP2A2_YEAST (10-309): 0: 514: 76.67
+	Sc
		594323 TCPD_YEAST (22-539): 0: 570: 59.20		PP11_YEAST (11-309): 1.47e-137: 393: 57.71
+	Sc
		594322 TCPG_YEAST (16-537): 0: 527: 31.77		PP11_YEAST (11-309): 1.47e-137: 393: 57.71
+	Sc
		594334 TCPH_YEAST (10-539): 0: 527: 30.73		PP11_YEAST (11-309): 1.47e-137: 393: 57.71
+	Sc
		594329 TCPE_YEAST (25-536): 4.35e-91: 291: 35.05		PP11_YEAST (11-309): 1.47e-137: 393: 57.71