HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

Property	Details
Experiments	26496610, 28514442, 31980649, 33961781, 35271311, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Hs			1 482
+	Hs
		826651 TCPG_HUMAN (12-537): 0: 553: 33.40		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		826803 TCPG_HUMAN (12-537): 0: 553: 33.40		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1038670 TCPH_HUMAN (12-538): 0: 549: 32.34		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		821200 TCPE_HUMAN (13-535): 0: 540: 37.88		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		821342 TCPE_HUMAN (13-535): 0: 540: 37.88		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		177239 TCPD_HUMAN (1-539): 0: 602: 100.00		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sc
		693018 TCPD_YEAST (22-539): 0: 570: 59.20		RPD3_YEAST (8-421): 0: 580: 61.48
+	Hs
		177233 TCPG_HUMAN (12-537): 0: 553: 33.40		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177367 TCPH_HUMAN (12-538): 0: 549: 32.34		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177231 TCPE_HUMAN (13-535): 0: 540: 37.88		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sc
		693035 TCPH_YEAST (10-539): 0: 527: 30.73		RPD3_YEAST (8-421): 0: 580: 61.48
+	Sp
		140614 TCPD_SCHPO (23-539): 0: 548: 65.90		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sp
		140638 TCPH_SCHPO (15-538): 0: 540: 30.83		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sp
		140519 TCPG_SCHPO (22-537): 0: 537: 32.76		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		760907 TCPD_YEAST (22-539): 0: 570: 59.20		HOS2_YEAST (10-411): 2.72e-171: 491: 50.00
+	Sp
		140725 TCPE_SCHPO (13-538): 0: 534: 35.03		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Hs
		843419 TCPD_HUMAN (1-539): 0: 602: 100.00		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		826927 TCPG_HUMAN (12-537): 0: 553: 33.40		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		1306720 TCPH_HUMAN (12-538): 0: 549: 32.34		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		821448 TCPE_HUMAN (13-535): 0: 540: 37.88		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78