HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.616

Property	Details
Experiments	28514442, 33961781, 23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Hs			1 347
+	Hs
		843190 TCPD_HUMAN (1-539): 0: 602: 100.00		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		177239 TCPD_HUMAN (1-539): 0: 602: 100.00		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		826651 TCPG_HUMAN (12-537): 0: 553: 33.40		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		1038670 TCPH_HUMAN (12-538): 0: 549: 32.34		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		826813 TCPG_HUMAN (12-537): 0: 553: 33.40		HDA11_HUMAN (1-347): 1.17e-140: 403: 100.00
+	Sc
		693018 TCPD_YEAST (22-539): 0: 570: 59.20		RPD3_YEAST (2-340): 1.99e-131: 383: 22.95
+	Mm
		945920 TCPH_MOUSE (12-538): 0: 556: 31.78		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Hs
		821200 TCPE_HUMAN (13-535): 0: 540: 37.88		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Sc
		760907 TCPD_YEAST (22-539): 0: 570: 59.20		HOS2_YEAST (3-331): 6.58e-124: 365: 21.43
+	Hs
		821140 TCPE_HUMAN (13-535): 0: 540: 37.88		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		826803 TCPG_HUMAN (12-537): 0: 553: 33.40		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		177233 TCPG_HUMAN (12-537): 0: 553: 33.40		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		177367 TCPH_HUMAN (12-538): 0: 549: 32.34		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		821342 TCPE_HUMAN (13-535): 0: 540: 37.88		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		177231 TCPE_HUMAN (13-535): 0: 540: 37.88		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		843419 TCPD_HUMAN (1-539): 0: 602: 100.00		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Hs
		826927 TCPG_HUMAN (12-537): 0: 553: 33.40		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Hs
		1306720 TCPH_HUMAN (12-538): 0: 549: 32.34		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Sp
		140614 TCPD_SCHPO (23-539): 0: 548: 65.90		PHD1_SCHPO (134-307): 1.94e-15: 79: 31.69
+	Sp
		140638 TCPH_SCHPO (15-538): 0: 540: 30.83		PHD1_SCHPO (134-307): 1.94e-15: 79: 31.69