HitPredict

Interactor 1: ANX11 (P50995)
Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50)
Gene: ANXA11

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30024968, 32900848
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0023026 - MHC class II protein complex binding GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 236
+	Hs
		451780 ANXA4_HUMAN (187-505): 3.35e-177: 502: 56.74		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		436078 ANXA6_HUMAN (203-503): 7.24e-65: 224: 29.34		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		436067 ANXA6_HUMAN (203-503): 7.24e-65: 224: 29.34		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		589173 ANXA7_HUMAN (357-504): 1.24e-22: 102: 34.46		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00