HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: ZBT16 (Q05516)
Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF)
Gene: ZBTB16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.596

Property	Details
Experiments	32814053, 17500595
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0032991 - protein-containing complex GO:0043065 - positive regulation of apoptotic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 3142 Hs			1 673
+	Hs
		843502 HD_HUMAN (1-3142): 0: 5724: 100.00		ZNF91_HUMAN (141-673): 1.55e-169: 518: 21.67
+	Hs
		844074 HD_HUMAN (1-3142): 0: 5724: 100.00		ZN180_HUMAN (135-673): 9.59e-157: 470: 22.32
+	Hs
		843689 HD_HUMAN (1-3142): 0: 5724: 100.00		ZFP2_HUMAN (205-653): 4.68e-150: 444: 27.71
+	Hs
		843958 HD_HUMAN (1-3142): 0: 5724: 100.00		ZN436_HUMAN (369-653): 1.03e-139: 418: 37.41
+	Hs
		843776 HD_HUMAN (1-3142): 0: 5724: 100.00		ZN557_HUMAN (385-625): 7.58e-50: 181: 38.17