Interactor 1: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Interactor 2: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 26186194, 32296183, 8668200, 29395067, 26949739, 21653829, 7489725, 24778252, 24981860, unassigned1973, 32525608
Identification Methods affinity chromatography technology, two hybrid, biochemical, proximity labelling technology, pull down, tandem affinity purification, two hybrid fragment pooling approach, cross-linking study, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Agenet~Agenet, Agenet~KH_9, Agenet~Tudor_FRX1, KH_1~KH_1, KH_9~Tudor_FRX1
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001934 - positive regulation of protein phosphorylation
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus
and 29 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 621
Hs

1 632
+ Mm
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+ Dm

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Last updated: 15 Jul 2024