HitPredict

Interactor 1: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	21653829, 35271311
Identification Methods	two hybrid, affinity chromatography technology, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0140694 - non-membrane-bounded organelle assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 621 Hs			1 523
+	Hs
		843687 FXR1_HUMAN (1-621): 0: 998: 100.00		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613383 FXR1_HUMAN (1-621): 0: 998: 100.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Mm
		665753 FXR1_MOUSE (1-621): 0: 950: 88.77		PABP1_MOUSE (4-522): 6.83e-70: 237: 14.16
+	Hs
		843649 FXR1_HUMAN (1-621): 0: 998: 100.00		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		844167 FXR2_HUMAN (4-621): 0: 840: 57.75		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		844075 FXR2_HUMAN (4-621): 0: 840: 57.75		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613384 FXR2_HUMAN (4-621): 0: 840: 57.75		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Mm
		1142832 FXR1_MOUSE (1-621): 0: 950: 88.77		ELAV4_MOUSE (41-156): 2.45e-16: 82.6: 32.79
+	Mm
		1141834 FXR1_MOUSE (1-621): 0: 950: 88.77		ELAV2_MOUSE (84-156): 1.3e-13: 74.1: 31.65
+	Mm
		936677 FXR1_MOUSE (1-621): 0: 950: 88.77		ELAV1_MOUSE (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		516477 FMR1_HUMAN (1-506): 0: 599: 51.13		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		613429 FMR1_HUMAN (1-506): 0: 599: 51.13		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Mm
		1143076 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		ELAV4_MOUSE (41-156): 2.45e-16: 82.6: 32.79
+	Mm
		1141837 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		ELAV2_MOUSE (84-156): 1.3e-13: 74.1: 31.65
+	Mm
		936690 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		ELAV1_MOUSE (84-156): 3.1e-13: 72.6: 29.11
+	Mm
		1141840 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		ELAV3_MOUSE (84-151): 6.6e-13: 72.2: 32.43
+	Mm
		729493 FMR1_MOUSE (1-506): 0: 599: 51.04		ELAV4_MOUSE (41-156): 2.45e-16: 82.6: 32.79
+	Mm
		729486 FMR1_MOUSE (1-506): 0: 599: 51.04		ELAV2_MOUSE (84-156): 1.3e-13: 74.1: 31.65
+	Mm
		729447 FMR1_MOUSE (1-506): 0: 599: 51.04		ELAV1_MOUSE (84-156): 3.1e-13: 72.6: 29.11
+	Mm
		729487 FMR1_MOUSE (1-506): 0: 599: 51.04		ELAV3_MOUSE (84-151): 6.6e-13: 72.2: 32.43