HitPredict

Interactor 1: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.637

Property	Details
Experiments	29395067, 21653829
Identification Methods	proximity labelling technology, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0098978 - glutamatergic synapse
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 435
+	Hs
		843885 FXR1_HUMAN (1-621): 0: 998: 100.00		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		844186 FXR2_HUMAN (4-621): 0: 840: 57.75		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		844223 FXR2_HUMAN (4-621): 0: 840: 57.75		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Mm
		1142869 FXR1_MOUSE (1-621): 0: 950: 88.77		STON2_MOUSE (146-433): 1.11e-60: 213: 22.85
+	Hs
		989049 FMR1_HUMAN (1-506): 0: 599: 51.13		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00