HitPredict

Interactor 1: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Interactor 2: JIP3 (Q9UPT6)
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)
Gene: MAPK8IP3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21653829
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030426 - growth cone GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 1336
+	Hs
		725116 FXR1_HUMAN (1-621): 0: 998: 100.00		MYH10_HUMAN (243-769): 2.9e-24: 113: 8.89
+	Hs
		724719 FXR1_HUMAN (1-621): 0: 998: 100.00		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Hs
		148549 FXR1_HUMAN (1-621): 0: 998: 100.00		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		843871 FXR1_HUMAN (1-621): 0: 998: 100.00		AKAP9_HUMAN (45-563): 1.97e-11: 71.2: 13.56
+	Mm
		1142850 FXR1_MOUSE (1-621): 0: 950: 88.77		AKAP9_MOUSE (3-677): 5.56e-10: 66.6: 13.51
+	Hs
		725117 FXR2_HUMAN (4-621): 0: 840: 57.75		MYH10_HUMAN (243-769): 2.9e-24: 113: 8.89
+	Hs
		148550 FXR2_HUMAN (4-621): 0: 840: 57.75		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		844213 FXR2_HUMAN (4-621): 0: 840: 57.75		AKAP9_HUMAN (45-563): 1.97e-11: 71.2: 13.56
+	Hs
		988940 FMR1_HUMAN (1-506): 0: 599: 51.13		MRCKA_HUMAN (2-407): 2.77e-19: 96.9: 12.93
+	Mm
		1174194 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		AKAP9_MOUSE (3-677): 5.56e-10: 66.6: 13.51
+	Hs
		989083 FMR1_HUMAN (1-506): 0: 599: 51.13		AKAP9_HUMAN (45-563): 1.97e-11: 71.2: 13.56
+	Mm
		729526 FMR1_MOUSE (1-506): 0: 599: 51.04		AKAP9_MOUSE (3-677): 5.56e-10: 66.6: 13.51