HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 28514442, 30217970, 8668200, 29395067, 24981860, 33961781, 7489725, 24778252, 25416956, 32296183, 26949739, 10567518, 21653829, 24722188
Identification Methods affinity chromatography technology, two hybrid, pull down, proximity labelling technology, biochemical, two hybrid prey pooling approach, two hybrid array, cross-linking study, two hybrid pooling approach, validated two hybrid and 2 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Agenet~Agenet, Agenet~KH_9, Agenet~Tudor_FRX1, KH_1~KH_1, KH_9~Tudor_FRX1
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001934 - positive regulation of protein phosphorylation
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus
and 21 others

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Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 673
Hs

1 632
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+ Dm

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Last updated: 15 Jul 2024