HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0010494 - cytoplasmic stress granule GO:0043488 - regulation of mRNA stability
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 1133
+	Hs
		843728 FXR1_HUMAN (14-673): 0: 798: 51.34		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		844252 FXR2_HUMAN (1-673): 0: 1004: 100.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		843915 FXR1_HUMAN (14-673): 0: 798: 51.34		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		988938 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		989130 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		RC3H2_HUMAN (1-1107): 0: 1494: 51.72