HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: LS14A (Q8ND56)
Protein LSM14 homolog A (Protein FAM61A) (Protein SCD6 homolog) (Putative alpha-synuclein-binding protein) (AlphaSNBP) (RNA-associated protein 55A) (hRAP55) (hRAP55A)
Gene: LSM14A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	29395067, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule GO:0017148 - negative regulation of translation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 463
+	Hs
		844221 FXR2_HUMAN (1-673): 0: 1004: 100.00		LS14B_HUMAN (2-401): 1.81e-74: 240: 45.70
+	Hs
		843801 FXR1_HUMAN (14-673): 0: 798: 51.34		LS14A_HUMAN (1-463): 2.65e-117: 353: 100.00
+	Mm
		102653 FXR1_MOUSE (14-673): 0: 981: 62.83		G3X972_MOUSE (78-295): 2.1e-11: 68.4: 13.62
+	Mm
		57191 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		CHD7_MOUSE (63-378): 3.89e-09: 61.5: 9.58
+	Hs
		989014 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		LS14A_HUMAN (1-463): 2.65e-117: 353: 100.00
+	Mm
		57183 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		CHD7_MOUSE (63-378): 3.89e-09: 61.5: 9.58