HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: P121A (Q96HA1)
Nuclear envelope pore membrane protein POM 121 (Nuclear envelope pore membrane protein POM 121A) (Nucleoporin Nup121) (Pore membrane protein of 121 kDa)
Gene: POM121

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	25416956, 21516116
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051028 - mRNA transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 1249
+	Hs
		727226 FXR2_HUMAN (1-673): 0: 1004: 100.00		NU214_HUMAN (91-1211): 3.61e-15: 83.5: 12.90
+	Hs
		844303 FXR2_HUMAN (1-673): 0: 1004: 100.00		PRC2C_HUMAN (2-1138): 9.15e-15: 82.1: 9.62
+	Mm
		1142853 FXR1_MOUSE (14-673): 0: 981: 62.83		PRC2A_MOUSE (72-1249): 6.2e-09: 63: 9.34
+	Mm
		1111986 FXR1_MOUSE (14-673): 0: 981: 62.83		PRC2C_MOUSE (57-1248): 7.45e-09: 62.6: 8.67
+	Hs
		843980 FXR1_HUMAN (14-673): 0: 798: 51.34		PRC2C_HUMAN (2-1138): 9.15e-15: 82.1: 9.62
+	Mm
		1207085 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		ANR17_MOUSE (297-1179): 5.72e-25: 115: 14.51
+	Mm
		761861 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		ZO1_MOUSE (117-897): 6.86e-22: 105: 12.53
+	Mm
		292197 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		BSN_MOUSE (71-1159): 3.07e-10: 67.1: 10.05
+	Mm
		1186751 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		PRC2A_MOUSE (72-1249): 6.2e-09: 63: 9.34
+	Mm
		1111989 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		PRC2C_MOUSE (57-1248): 7.45e-09: 62.6: 8.67
+	Mm
		729583 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		ANR17_MOUSE (297-1179): 5.72e-25: 115: 14.51
+	Mm
		93374 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		TENS1_MOUSE (215-1205): 5.03e-24: 112: 13.09
+	Mm
		729419 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		ZO1_MOUSE (117-897): 6.86e-22: 105: 12.53
+	Hs
		989216 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		PRC2C_HUMAN (2-1138): 9.15e-15: 82.1: 9.62
+	Mm
		292190 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		BSN_MOUSE (71-1159): 3.07e-10: 67.1: 10.05
+	Mm
		729533 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		PRC2A_MOUSE (72-1249): 6.2e-09: 63: 9.34
+	Mm
		729462 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		PRC2C_MOUSE (57-1248): 7.45e-09: 62.6: 8.67