HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 24778252
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule GO:0051028 - mRNA transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 482
+	Hs
		844042 FXR2_HUMAN (1-673): 0: 1004: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		843962 FXR1_HUMAN (14-673): 0: 798: 51.34		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		843648 FXR1_HUMAN (14-673): 0: 798: 51.34		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		843665 FXR1_HUMAN (14-673): 0: 798: 51.34		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Mm
		956347 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		G3BP2_MOUSE (1-482): 3.86e-108: 331: 98.34
+	Mm
		729455 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		G3BP2_MOUSE (1-482): 3.86e-108: 331: 98.34
+	Hs
		989190 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		988857 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		988899 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43